但是氨基酸及其衍生物的溶解性差，这很大程度上限制了其应用的翻译：But poor solubility of amino acids and their derivatives, this is to a large extent limited apply 什么意思？中文翻译英文，英文翻译中文，怎么说？

青云英语翻译

But the poor solubility of amino acids and their derivatives, which largely limits its application

But poor solubility of amino acids and their derivatives, this is to a large extent limited apply

But the amino acid and the derivative solubility is bad, this has limited its application to a great extent

But amino acid and its derivatives of solvent, poor, and this greatly limits its application

But poor solubility of amino acids and their derivatives, this is to a large extent limited apply